Related Experiment Video

Updated: Jul 20, 2026

Isolation of Mouse Respiratory Epithelial Cells and Exposure to Experimental Cigarette Smoke at Air Liquid Interface
10:47

Isolation of Mouse Respiratory Epithelial Cells and Exposure to Experimental Cigarette Smoke at Air Liquid Interface

Published on: February 21, 2011

The respiratory effects of regular cigarette smoking in women. A five-year prospective study

C R Woolf, N Zamel

    Chest
    |November 1, 1980
    PubMed

    Over a five-year period a consistent habit of smoking or nonsmoking was maintained by 302 women (aged 25 to 54 years at the beginning of the study). There were 130 nonsmokers, 40 ex-smokers, and 15 light, 46 moderate, and 71 heavy smokers. Smokers without serious disability who had stopped smoking had a very low prevalence of respiratory symptoms and showed worsening of pulmonary function over the years similar to life-long non-smokers. Although there is a dose-related response to cigarettes, individual susceptibility also plays an important role in determining the respiratory effect of smoking. A range for change in ventilatory function over a five-year period in apparently healthy nonsmoking women is provided. Using this range, it is possible to identify susceptible smokers who show deterioration in ventilatory function that is more rapid than normal. Repeated spirometric studies may be useful in selecting a group at greatest risk of developing later disabling chronic obstructive pulmonary disease.

    More Related Videos

    Impact Assessment of Repeated Exposure of Organotypic 3D Bronchial and Nasal Tissue Culture Models to Whole Cigarette Smoke09:50

    Impact Assessment of Repeated Exposure of Organotypic 3D Bronchial and Nasal Tissue Culture Models to Whole Cigarette Smoke

    Published on: February 12, 2015

    Cigarette Smoke Exposure in Mice using a Whole-Body Inhalation System06:07

    Cigarette Smoke Exposure in Mice using a Whole-Body Inhalation System

    Published on: October 22, 2020

    Related Concept Videos

    Observational Studies01:11

    Observational Studies

    Observational studies are a type of analytical study where researchers observe events without any interventions. In other words, the researcher does not influence the response variable or the experiment's outcome.
    There are three types of observational studies – Prospective, retrospective, and cross-sectional.
    Prospective Study
    Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One example of...
    Chronic Obstructive Pulmonary Disease-I: Introduction01:20

    Chronic Obstructive Pulmonary Disease-I: Introduction

    Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
    Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

    Chronic Obstructive Pulmonary Disease-II: Pathophysiology

    Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
    Chronic Inflammation
    Statistical Methods for Analyzing Epidemiological Data01:25

    Statistical Methods for Analyzing Epidemiological Data

    Epidemiological data primarily involves information on specific populations' occurrence, distribution, and determinants of health and diseases. This data is crucial for understanding disease patterns and impacts, aiding public health decision-making and disease prevention strategies. The analysis of epidemiological data employs various statistical methods to interpret health-related data effectively. Here are some commonly used methods:
    Stress Prevention and Stress Management Techniques IV01:26

    Stress Prevention and Stress Management Techniques IV

    Stress often leads to unhealthy habits like smoking, excessive drinking, and overeating, which offer short-term relief but ultimately increase long-term health risks. These behaviors create a cycle that temporarily lowers stress levels but can result in severe long-term health consequences. Breaking these habits is essential to reduce the risk of chronic diseases and improve overall well-being. Three primary changes that support better health include quitting smoking, reducing alcohol intake,...
    Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

    Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

    Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...