Related Experiment Videos
[Paraproteinaemic coma in multiple myeloma (author's transl)]
Abstract:
The diagnosis of paraproteinaemic coma was made in 5 out of 74 patients with plasmocytoma. Compared with the other patients these 5 showed a nearly twofold increase of total serum and CSF protein concentration, a higher percentage of plasma cells in sternal marrow and extreme hypergamma-globulinaemia in the immunoelectrophoresis. In both groups CSF and serum amino acid concentrations showed no pathological changes. Psychopathologically the patients with paraproteinaemic coma showed the picture of an exogenous psychosyndrome. Electroencephalography demonstrated moderate general disturbances.
Insights
Paraproteinaemic coma, a rare complication in plasmocytoma patients, is linked to elevated serum and cerebrospinal fluid protein levels. This condition presents with specific neurological and electroencephalographic changes.
Area of Science:
- Neurology
- Oncology
- Clinical Chemistry