Perforation of the sigmoid colon simulating acute appendicitis
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Updated: Oct 21, 2026

Murine Colitis Modeling using Dextran Sulfate Sodium (DSS)
Published on: January 19, 2010
Abstract:
Diverticulitis and carcinoma with abscess formation following perforation of the redundant sigmoid colon was erroneously diagnosed as acute appendicitis in nine patients over a period of five years. As te inflammatory process develops in the right lower quadrant of the abdomen, lack of previous colonic pathology may lead to a misdiagnosis, usually of acute appendicitis. It should be borne in mind, however, that acute appendicitis decreases with age, whereas diverticula and carcinomas increase, and that the sigmoid colon is often a redundant organ with a tendency to migrate to the right side of the abdomen. In elderly patients with acute right abdominal pathology, it is important to operate through a transrectal or paramedian incision. A two-stage operation is preferable to a three-stage one.
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