Serological comparison between Histophilus ovis, Actinobacillus seminis and Brucella ovis

The serological relationships between 4 strains of Histophilus ovis, the neotype strain of Actinobacillus seminis and Brucella ovis were examined using a cross-absorption complement-fixation technique. It was found that the 4 strains of H. ovis were serologically homologous and that an incomplete relationship existed between these organisms and A. seminis. Anteriserums prepared against one strain of H. ovis and the strain of A. seminis gave a weak, apparently non-specific cross-reaction with Br. ovis antigen. The practical significance of these results is discussed.