Mass spectrometric differentiation of cannabinoid-containing samples

A direct-inlet probe mass spectrometry/multiple regression procedure is described for the confirmation of the presence of cannabinoids and the comparison of various cannabinoid-containing samples. The relative intensities of selected mass units are first established on control cannabinoids. These standards are then regressed on mass spectra of samples of interest. High values of coefficients of determination are used to confirm the presence of cannabinoid mixtures; regression coefficients are used for sample comparisons.