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An exfoliative skin disease in guinea pigs due to Staphylococcus aureus
Laboratory Animal Science
|June 1, 1980
Abstract:
A unique skin disease hitherto unreported was observed in 23 guinea pigs from a colony of 180 animals. The disease was characterized clinically by erythema on the skin of the ventral abdomen and thorax and subsequent exfoliation of the epidermis. The disease occurred most commonly in pregnant females (19 cases). Histological examinations revealed an epidermal cleavage through the stratum granulosum. Staphylococcus aureus was isolated from affected animals, and the disease was experimentally induced in guinea pigs inoculation of the skin with two strains of Staphylococcus aureus.