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Bronchial malignant melanoma

Z Weshler, A Sulkes, J Kopolovitch

Journal of Surgical Oncology

|January 1, 1980

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Malignant melanoma can present as an endobronchial lesion causing lung collapse, which may temporarily respond to radiation therapy. Widespread metastases often develop rapidly, highlighting the aggressive nature of this rare presentation.

Area of Science:

Pulmonology
Oncology
Pathology

Background:

Malignant melanoma, a cancer of pigment-producing cells, rarely metastasizes to the bronchus.
Endobronchial tumors can cause significant airway obstruction and lung collapse (atelectasis).

Observation:

A case of malignant melanoma presenting as an endobronchial lesion in the left main bronchus was observed.
The lesion caused complete atelectasis of the left lung.

Findings:

Radiation therapy led to temporary resolution of the endobronchial lesion and atelectasis.
Widespread metastases developed shortly after initial treatment, indicating aggressive disease progression.

Implications:

This case underscores the importance of considering rare diagnoses like endobronchial melanoma in the differential diagnosis of obstructive lung lesions.

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