[Methodologic problems concerning pharmacology effect on bronchomotricity in asthma (Raw, V/V) (author's transl)]

Study of spirometric, flow-rate and Raw modifications in three groups of 5 to 8 asthmatic patients (stage I or II) before and after acetylcholine and pneumallergen (dust) action is made. The same modifications were studied on the action of dust before and after a chemical protector effect. In two control groups the following parameters were verified: 1) the stability of Raw and V/V (normal subjects: 8); 2) the reproductibility of the acetylcholine bronchospasm, before and after the action of chemical protector (asthmatic patients: 11). Some considerations about the methodology in the practice of bronchomotricity data are submitted.