[Neurogenic mechanisms of the idiopathic edema syndrome]

Clinical and experimental studies on cerebral components, emotional-motivation--personality sphere, vegetative nervous system and their relationships were carried out in 31 women suffering from idiopathic edema. Three neurogenic factors (psychological, hypothalamus dysfunction and brain homeostasis disorder) influence the disease pathogenesis. It has been demonstrated that these factors correlate well with endocrine and vegetative disorders being the pathological basis of the disease. It is concluded that the neurogenic factors play a different role in the disease pathogenesis. Severe forms of the disease are characterized by cerebro-endocrine mechanisms of the fluid retention, and mild cases by psychovegetative ones.