Doxycycline in the treatment of chlamydial urethritis: a therapeutic study

The effect of doxycycline treatment was studied in 46 men with chlamydial non-gonococcal urethritis. Treatment with 200 mg doxycycline daily for 10 days rendered 22 of 22 patients free of urethritis. The treatment had no effect on the complications of urethritis like prostatitis and Reiter's syndrome. In the other group where 200 mg doxycycline was given on the first day and 100 mg on the subsequent days for 8 days, urethritis was resolved in 18 of 22 patients. C. trachomatis was not re-isolated from any of the patients after doxycycline treatment.