[Comparative study of the proteins of influenza virus type A nucleoproteins]

A comparative study of protein of nucleoproteins (NP-protein) of influenza A viruses by peptide mapping shows its variability to be small within one drifting series and quite marked in strains belonging to different sero-types. In oligopeptide maps of NP-proteins of viruses of the Hong Kong (H3N2) series there is a typical group of spots differing them from oligopeptide maps of NP-proteins of viruses of other serotypes, particularly of the preceeding serotype H2N2 and the viruses related by hemagglutinin: A/duck/Ukraine/63 (Hav7Neq2) and A/horse/Miami/63 (Heq2Neq2). NP-proteins of the old A/swine/Iowa/30 and new A/New Jersey/76 strains of swine influenza viruses belonging to the same serotype Hsw1N1 differ from each other but are similar to NP-proteins of viruses of H0N1 and H1N1 serotypes, respectively.