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[A suggestion for the uniform laboratory diagnosis of hemophilia]
The laboratory diagnosis of the haemophilia is performed in a different way in the individual laboratories. Differences in the selection and the performance of the methods used render differences in evidence, comparability and expenditure of time. The following proposition for a unitary laboratory diagnostics of haemophilia is made: 1. performance of a basic programme, 2. localisation of the coagulation defect with the help of the PTT using correction plasmas, 3. quantitative estimation of factors (possibly inhibitors) after one-step method, in which cases usual test sets of instruments with standardized directive for the performance are prerequisite for comparable results and a subdivision in degrees of severity.
The laboratory diagnosis of the haemophilia is performed in a different way in the individual laboratories. Differences in the selection and the performance of the methods used render differences in evidence, comparability and expenditure of time. The following proposition for a unitary laboratory diagnostics of haemophilia is made: 1. performance of a basic programme, 2. localisation of the coagulation defect with the help of the PTT using correction plasmas, 3. quantitative estimation of factors (possibly inhibitors) after one-step method, in which cases usual test sets of instruments with standardized directive for the performance are prerequisite for comparable results and a subdivision in degrees of severity.