HDL-increasing effect of cyclofenil

Nineteen patients with low levels of HDL as measured by APO-AI have been treated with cyclofenil (a non-steroid stilboestrol isomer with very low oestrogenic effects) as the only form of therapy. The therapy elicited a highly significant rise of about 15% in HDL levels. A slight increase in transaminases occurred in 6 patients but was reversible without terminating therapy.