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Effect of selective coronary arteriography on left ventricular volumes and ejection fraction in man
Insights
Selective coronary arteriography increases left ventricular end-diastolic pressure but does not affect left ventricular volumes or ejection fraction in patients. This finding holds true even for individuals with compromised cardiac function.
Area of Science:
- Cardiology
- Diagnostic Imaging
Background:
- Selective coronary arteriography is a key diagnostic tool in cardiology.
- Assessing its immediate impact on left ventricular function is crucial for patient management.
Purpose of the Study:
- To evaluate the influence of selective coronary arteriography on left ventricular (LV) volumes and ejection fraction.
- To determine if the procedure alters hemodynamic parameters in patients with cardiac diseases.
Main Methods:
- 30 patients with various cardiac conditions underwent LV volume and ejection fraction assessment before and after selective coronary arteriography.
- Two methods were used: contrast left ventriculography (19 patients) and multigated equilibrium blood pool imaging (11 patients).
Main Results:
- Left ventricular end-diastolic pressure significantly increased post-procedure.
- No significant changes were observed in end-diastolic volume index, end-systolic volume index, or ejection fraction.
- Systemic arterial pressure and heart rate remained stable throughout the assessments.
Conclusions:
- Selective coronary arteriography consistently elevates left ventricular end-diastolic pressure.
- The procedure does not impact left ventricular volumes or ejection fraction, irrespective of baseline cardiac function.
Abstract:
This study was performed to assess the influence of selective coronary arteriography on left ventricular volumes and ejection fraction in man. In 30 patients with assorted cardiac diseases, left ventricular end-diastolic and end-systolic volumes and ejection fraction were quantitated immediately before and after selective coronary arteriography. In 19 patients (Group A), contrast left ventriculography was performed immediately before and after selective coronary arteriography. In the remaining 11 patients (Group B), multigated equilibrium blood pool imaging was performed just before and after coronary arteriography. In both groups, mean systemic arterial pressure and heart rate did not change from just before the first to immediately before the second assessment of left ventricular volumes and ejection fraction, but left ventricular end-diastolic pressure increased. End-diastolic and end-systolic volume indexes, and ejection fraction did not change from just before to immediately after selective coronary arteriography. Therefore, selective coronary arteriography (1) consistently causes an increase in left ventricular end-diastolic pressure but (2) exerts no effect on left ventricular volumes and ejection fraction, even in patients with severely compromised left ventricular function.