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Miliary tuberculosis in association with chronic cutaneous tuberculosis

D E Bateman, W Makepeace, M Lesna

    The British Journal of Dermatology
    |November 1, 1980
    PubMed
    Summary

    This case report details miliary tuberculosis co-occurring with two skin tuberculosis forms, despite a negative Heaf tuberculin test. Early diagnosis was aided by skin biopsy and culture, highlighting an unusual negative tuberculin test finding.

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    Area of Science:

    • Immunology
    • Infectious Diseases
    • Dermatology

    Background:

    • Miliary tuberculosis (TB) is a disseminated form of TB.
    • Cutaneous tuberculosis presents diverse clinical manifestations.
    • Tuberculin skin tests are standard for TB screening.

    Observation:

    • A patient presented with miliary TB and two distinct types of cutaneous TB.
    • The patient exhibited a negative result on the Heaf tuberculin test.
    • Skin biopsy and culture were utilized for diagnostic purposes.

    Findings:

    • Skin biopsy and culture proved valuable for early diagnosis of miliary and cutaneous TB.
    • The co-occurrence of miliary TB with multiple cutaneous forms is rare.
    • A negative Heaf tuberculin test in active TB is an unusual finding, challenging diagnostic norms.

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    Implications:

    • This case underscores the importance of considering TB in patients with unexplained skin lesions and systemic symptoms.
    • Diagnostic methods like skin biopsy and culture are crucial when standard tests yield unexpected results.
    • Further investigation into factors influencing tuberculin test reactivity in disseminated TB is warranted.