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Application of Stopped-flow Kinetics Methods to Investigate the Mechanism of Action of a DNA Repair Protein
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Application of Stopped-flow Kinetics Methods to Investigate the Mechanism of Action of a DNA Repair Protein

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A phase diagram of the binding of mismatched duplex DNAs to hydroxyapatite

G M Fox, J Umeda, R K Lee

    Biochimica Et Biophysica Acta
    |October 17, 1980
    PubMed

    Abstract:

    The hydroxyapatite binding properties of imperfectly base-paired DNA have been investigated and summarized in a phase diagram. This diagram defines the conditions at which thermal elution results in both denaturation and desorption of mismatched duplex DNA from hydroxyapatite.

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