Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cardiac valve replacement in elderly patients

W R Jamieson, D M Thompson, A I Munro

    Canadian Medical Association Journal
    |October 7, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Endothelial Cells Exposed to Fluid Shear Stress Support Diffusion Based Maturation of Adult Neural Progenitor Cells.

    Cellular and molecular bioengineering·2019
    Same author

    Combination avelumab and utomilumab immunotherapy can induce diabetic ketoacidosis.

    Diabetes & metabolism·2017
    Same author

    Robust neurite extension following exogenous electrical stimulation within single walled carbon nanotube-composite hydrogels.

    Acta biomaterialia·2016
    Same author

    Commissural region dehiscence from the stent post of Carpentier-Edwards bioprosthetic cardiac valves.

    Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology·2015
    Same author

    Neurite outgrowth on electrospun PLLA fibers is enhanced by exogenous electrical stimulation.

    Journal of neural engineering·2014
    Same author

    The inheritance of genetic markers in microspore-derived plants of barley Hordeum vulgare L.

    TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·2013

    Cardiac valve replacement in elderly patients shows similar indications to the general population. While early mortality is higher, long-term functional status is excellent, with aortic valve replacement yielding better results than mitral.

    Area of Science:

    • Cardiology
    • Geriatric Medicine
    • Cardiac Surgery

    Background:

    • Elderly patients represent a growing demographic undergoing cardiac procedures.
    • Cardiac valve replacement is a critical intervention for valvular heart disease.

    Purpose of the Study:

    • To evaluate the outcomes of cardiac valve replacement in elderly patients (aged 65 and older).
    • To compare the results of aortic versus mitral valve replacement in this age group.

    Main Methods:

    • Retrospective analysis of 65 consecutive elderly patients undergoing cardiac valve replacement.
    • Comparison of early and late mortality, complications, and functional status with a younger cohort.
    • Assessment of actuarial survival rates based on valve type and patient demographics.

    Related Experiment Videos

    Main Results:

    • Elderly patients comprised 16% of all valve replacement cases.
    • Thirty-day mortality was 4.6% in the elderly versus 0.9% in younger patients.
    • Long-term functional status was excellent (NYHA Class I/II) for most survivors.
    • Late mortality was higher for mitral valve replacement (15.1% per patient-year) compared to aortic valve replacement (3.9% per patient-year).
    • Actuarial survival rates at 24 months were 88% for the total elderly group.
    • Aortic valve replacement showed more favorable outcomes than mitral valve replacement in the elderly.

    Conclusions:

    • Indications for cardiac valve replacement in the elderly are consistent with the general population.
    • Despite higher early risks, elderly patients achieve excellent long-term functional recovery after valve replacement.
    • Aortic valve replacement appears to be a more gratifying procedure than mitral valve replacement in elderly patients.