Synchronous bilateral renal cell carcinoma: total surgical excision

Area of Science:

• Oncology
• Nephrology
• Surgical Oncology

Background:

• Bilateral synchronous renal cell carcinoma is a rare clinical presentation.
• Management strategies for this condition require careful consideration due to bilateral involvement.

Purpose of the Study:

• To evaluate the outcomes of surgical management for patients with bilateral synchronous renal cell carcinoma.
• To compare the survival rates with those of unilateral renal cell carcinoma.

Main Methods:

• Retrospective analysis of 61 patients with bilateral synchronous renal cell carcinoma.
• Surgical interventions included total excision, renal parenchymal-sparing procedures, and extracorporeal tumor resection.
• Follow-up data were obtained directly from surgeons or patients.

Main Results:

• A 10% local tumor recurrence rate was observed.
• Fifty-one patients underwent kidney-sparing procedures; 17 had extracorporeal tumor resection.
• Ten patients required bilateral nephrectomy, with 4 undergoing subsequent renal transplantation.

Conclusions:

• The overall five-year survival rate for this cohort was 69%.
• This survival rate is notably better than that reported for unilateral renal cell carcinoma.
• Surgical management, including nephron-sparing approaches, can achieve favorable outcomes in bilateral renal cell carcinoma.