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Abstract:
An improved long-acting Norgestrel-T contraceptive device has been developed. The effects of different release levels of levonorgestrel on the endometrium were studied in a selected group of 42 subjects. A randomized comparative study of the clinical performance of Cu-T 200 and Ng-T devices was undertaken in 200 fertile women for 15 months. Quantitation of the menstrual blood loss was performed on a selected group of 20 users. This new Ng-T device proved highly effective in fertility control. It was associated with a significant reduction in the amount of menstrual blood loss and incidence of termination probabilities due to bleeding and pain.