Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Allometry formula: a cellular model

M J Katz

    Growth
    |June 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    The allometry formula y = bxk models organism growth by linking constants to cell division. This provides testable predictions about brain development differences across species and within humans.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Context-specific functions of Notch in Drosophila blood cell progenitors.

    Developmental biology·2020
    Same author

    Hydroxylation and translational adaptation to stress: some answers lie beyond the STOP codon.

    Cellular and molecular life sciences : CMLS·2016
    Same author

    Determining the structural stability of UiO-67 with respect to time: a solid-state NMR investigation.

    Chemical communications (Cambridge, England)·2016
    Same author

    The Statistical Modeling of Aging and Risk of Transition Project: Data Collection and Harmonization Across 11 Longitudinal Cohort Studies of Aging, Cognition, and Dementia.

    Observational studies·2015
    Same author

    Cognitive activities delay onset of memory decline in persons who develop dementia.

    Neurology·2009
    Same author

    Hippocampal neurochemistry, neuromorphometry, and verbal memory in nondemented older adults.

    Neurology·2008
    Same journal

    Some aspects of the role of hormonal and nutritional factors in skeletal growth and development.

    Growth·2014
    Same journal

    Lymphoid tissue and its relation to so-called normal lymphoid foci and to lymphomatosis; simplification of methods for quantitative analyses and its application to the turkey.

    Growth·2014
    Same journal

    Variations in body weight and organ; body-weight ratios of inbred lines of white Leghorn chickens in relation to mortality, especially from lymphomatosis.

    Growth·2014
    Same journal

    The effect of biotin on mitotic activity in the liver of the mouse.

    Growth·2014
    Same journal

    Superoxide dismutase, thermal respiratory acclimation, and growth in an earthworm, Eisenia foetida.

    Growth·2013
    Same journal

    A comparison of regeneration rates and metamorphosis in Triturus and Amblystoma.

    Growth·2010
    See all related articles

    Area of Science:

    • Developmental Biology
    • Comparative Anatomy
    • Quantitative Biology

    Background:

    • The simple allometry formula (y = bxk) is commonly used to model the relative growth of biological structures.
    • Understanding the biological basis of allometric constants can enhance the predictive power of these models.

    Purpose of the Study:

    • To propose an interpretation of the allometric constants b and k in terms of biological processes.
    • To derive experimentally testable predictions regarding differential brain development.

    Main Methods:

    • Interpreting the allometric constant 'b' as the relative number of germinal centers (cell division centers).
    • Interpreting the allometric constant 'k' as the relative frequency of cell division.
    • Applying these interpretations to predict differences in brain development.

    Related Experiment Videos

    Main Results:

    • The allometric constant 'b' can represent the relative abundance of germinal centers between two biological parts.
    • The allometric constant 'k' can represent the relative cell division rates between two biological parts.
    • This framework predicts that developing mammalian and avian brains may possess germinal centers absent in fish and reptiles.

    Conclusions:

    • The proposed interpretation of allometric constants offers a biologically grounded framework for studying relative growth.
    • This model yields specific, testable hypotheses about species-specific differences in developmental processes, such as brain growth.
    • Further research can validate these predictions by examining germinal centers and cell division rates in diverse species' developing brains.