Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Dose-response in case-control studies

G Berry

    Journal of Epidemiology and Community Health
    |September 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Analyzing lung cancer risk from asbestos exposure requires considering dose-response relationships. New methods for matched case-control studies, accounting for exposure levels and smoking, offer more accurate risk assessments.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Current level of technology use, health and eHealth literacy in older Canadians with a recent fracture-a survey in orthopedic clinics.

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2020
    Same author

    Banff Lung Report: Current knowledge and future research perspectives for diagnosis and treatment of pulmonary antibody-mediated rejection (AMR).

    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2018
    Same author

    Mesothelioma risk after 40 years since first exposure to asbestos: a pooled analysis.

    Thorax·2014
    Same author

    Skeletal health in adult patients with classic galactosemia.

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2012
    Same author

    Malignant mesotheliomas in former miners and millers of crocidolite at Wittenoom (Western Australia) after more than 50 years follow-up.

    British journal of cancer·2012
    Same author

    Primary cervical tracheal monophasic synovial sarcoma confirmed by SYT-SSX gene rearrangement.

    The Journal of laryngology and otology·2011
    Same journal

    Sociodemographic inequalities in non-small cell lung cancer (NSCLC) novel treatments: a national population-based cohort study.

    Journal of epidemiology and community health·2026
    Same journal

    Secular trends in primary care utilisation for mental health problems: a Norwegian register-based population-wide study.

    Journal of epidemiology and community health·2026
    Same journal

    Guide to recent advances in difference-in-differences methodology for population health studies.

    Journal of epidemiology and community health·2026
    Same journal

    From early to fewer first births: ADHD and family formation among young adults.

    Journal of epidemiology and community health·2026
    Same journal

    10-year mortality among first-time mothers involved in family court care proceedings in England: cohort study using linked administrative hospital, mortality and family court records.

    Journal of epidemiology and community health·2026
    Same journal

    Reply to: 'Does race have confounders?' by Loux and Wankum.

    Journal of epidemiology and community health·2026
    See all related articles

    Area of Science:

    • Epidemiology
    • Occupational Health
    • Environmental Health

    Background:

    • Case-control studies are crucial for investigating disease associations.
    • Assessing exposure extent strengthens evidence by enabling dose-response analysis.
    • Matched case-control studies require specific analytical methods.

    Purpose of the Study:

    • To illustrate methods for estimating dose-response relationships in case-control studies.
    • To analyze the association between lung cancer and chrysotile asbestos exposure.
    • To compare matched and unmatched analyses in case-control studies.

    Main Methods:

    • Applied regression-type models to lung cancer and asbestos exposure data.
    • Included smoking as a covariate in the analysis.

    Related Experiment Videos

  • Performed analyses both ignoring and accounting for matching.

    • Main Results:

    • Dose-response relationships between asbestos exposure and lung cancer risk were estimated.
    • Regression models incorporating exposure levels and smoking were fitted.
    • Matched and unmatched analyses yielded similar results in this specific instance.

    Conclusions:

    • Matched case-control studies should be analyzed accounting for matching.
    • Newly developed methodologies enhance the accuracy of matched study analyses.
    • Accurate analysis of matched case-control studies is essential for reliable epidemiological findings.