Lactose malabsorption in two sibling rhesus monkeys (Macaca mulatta)

Area of Science:

• Primate nutrition
• Gastroenterology
• Animal models

Background:

• Rhesus monkeys (Macaca mulatta) are widely used in biomedical research.
• Understanding dietary intolerances in animal models is crucial for experimental design.

Observation:

• Two sibling rhesus monkeys were observed to have adverse reactions to a lactose-containing formula.
• Clinical signs included severe diarrhea and significant weight loss.

Findings:

• The observed symptoms strongly suggest lactose intolerance in these rhesus monkeys.
• A lactose-free diet effectively resolved gastrointestinal distress and promoted weight gain.

Implications:

• This case highlights the potential for lactose intolerance in rhesus monkeys.
• Researchers using rhesus monkeys should consider dietary lactose as a variable.
• Further investigation into the prevalence and mechanisms of lactose intolerance in this species may be warranted.