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Related Experiment Videos

Pindolol-induced tremor

H Hod, J Har-Zahav, N Kaplinsky

    Postgraduate Medical Journal
    |May 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Fine tremors appeared in patients treated with pindolol, a beta-blocker. This paradoxical side effect, possibly due to the drug

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    Area of Science:

    • Pharmacology
    • Neurology
    • Clinical Medicine

    Background:

    • Beta-adrenoceptor-blockers are commonly used to treat various medical conditions.
    • These drugs are generally known for their tremor-suppressing effects.

    Observation:

    • Five patients developed fine tremors in their extremities after initiating pindolol treatment.
    • Tremors emerged between 6-72 hours after starting the medication.

    Findings:

    • The observed tremors resolved within 24-72 hours after discontinuing pindolol.
    • This paradoxical tremor presentation is attributed to pindolol's potent partial agonist activity.

    Implications:

    • This study highlights a previously undescribed side effect of pindolol.
    • Clinicians should be aware of the potential for pindolol to induce tremors, contrary to typical beta-blocker effects.