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Effects of halogenated benzenes on arylesterase activity in vivo and in vitro
Research Communications in Chemical Pathology and Pharmacology
|November 1, 1980
Abstract:
Hepatic arylesterase activity was induced by 1,2,4-trichlorobenzene, hexachlorobenzene, 1,2,4-tribromobenzene, and 1,3,5-tribromobenzene but not by 1,3,5-trichlorobenzene or hexabromobenzene. Serum arylesterase was not induced by any of the halogenated benzenes and was inhibited in vivo by 1,2,4-trichlorobenzene, hexachlorobenzene, and 1,3,5-tribromobenzene. It was also inhibited in vitro.