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Coagulation parameters and heparin levels in open-heart surgery

Research in Experimental Medicine. Zeitschrift Fur Die Gesamte Experimentelle Medizin Einschliesslich Experimenteller Chirurgie
|January 1, 1980
PubMed

Coagulation parameters were studied during open-heart surgery. Severe reduction of the platelet count and of several other clotting factors was observed. The half-rate of heparin varied threefold in the patients. This may indicate that the dosage of protamine chloride prior to the end of the surgical procedure has to be adjusted to the individual heparin levels.

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