[Paroxysmal changes in the electrochemical activity of the cerebral cortex on platinum electrodes]

In rabbits potentials were simultaneously led off from a platinum, a gold and a non-polarizable electrodes (implanted down to the brain surface) by means of a DC amplifier, and under certain conditions changes in the potential of the platinum electrode were recorded which we named "paroxismal changes of bioelectrochemical potential", PBEChP. They had typical parameters: negative sign; speed of process increase considerably exceeding the speed of its decline; amplitude within the range from hundreds of mcV to several mV; duration from fractions of a second to several seconds; high degree of locality (up to 1.5-2 mm2). They revealed a close connection with the background periodic oscillations of the bioelectrochemical potential and were intensified with presentation of different sensory stimuli. It is assumed that PBEChP may be related to some forms of seizure activity.