Related Experiment Video

Updated: Sep 11, 2026

Rabies Necropsy Techniques in Large and Small Animals
06:56

Rabies Necropsy Techniques in Large and Small Animals

Published on: July 30, 2019

Rabies encephaloradiculomyelitis. Case report

C C Lamas, A J Martinez, R Baraff

    Acta Neuropathologica
    |January 1, 1980
    PubMed

    Insights

    A carpenter died of rabies, a rare but fatal neurological disease. Postmortem examination confirmed the diagnosis, highlighting the need for vigilance in diagnosing meningoencephalitis.

    Area of Science:

    • Neurology
    • Pathology
    • Virology

    Background:

    • Rabies is a viral disease affecting the central nervous system.
    • It is typically transmitted through animal bites, but cases with no confirmed exposure exist.

    Observation:

    • A 50-year-old carpenter presented with symptoms consistent with meningoencephalitis.
    • The patient was hospitalized for 28 days in intensive care.
    • Diagnosis was confirmed postmortem via neuropathologic examination and immunofluorescence.

    Findings:

    • The case involved rabies without a confirmed animal exposure.
    • Clinical and neuropathologic findings were correlated.
    • Microscopic examination of central nervous system tissue was crucial for diagnosis.

    Implications:

    • Recognizing rabies is critical for patient diagnosis and management.
    • Protective measures for autopsy personnel are essential.
    • Rabies should be considered in the differential diagnosis of radiculomyelitis and meningoencephalitis.

    More Related Videos

    Whole Genome Sequencing for Rapid Characterization of Rabies Virus Using Nanopore Technology10:26

    Whole Genome Sequencing for Rapid Characterization of Rabies Virus Using Nanopore Technology

    Published on: August 18, 2023

    Postmortem Diagnosis of Rabies in Animals by the Updated, Multiplexed LN34 Real-Time Reverse Transcription-Polymerase Chain Reaction Assay09:54

    Postmortem Diagnosis of Rabies in Animals by the Updated, Multiplexed LN34 Real-Time Reverse Transcription-Polymerase Chain Reaction Assay

    Published on: May 2, 2025

    Related Concept Videos

    Rocky Mountain Spotted Fever01:26

    Rocky Mountain Spotted Fever

    Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
    Viral Meningitis01:18

    Viral Meningitis

    Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
    Rabies01:28

    Rabies

    Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...
    Arboviral Encephalitis01:25

    Arboviral Encephalitis

    Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
    Encephalitis l: Introduction01:19

    Encephalitis l: Introduction

    Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
    Encephalitis ll: Pathophysiology01:26

    Encephalitis ll: Pathophysiology

    Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...