Valvular xenograft and valvular xenobioprosthesis: Past, present, and future

At the present time, glutaraldehyde-preserved porcine valves appear to be a reasonable alternative in valvular replacement. The expected durability limit of 8-15 years with the models currently commercially available is counterbalanced by a lower risk of acute complications; particularly thromboembolism. This allows the patient to be free from drugs and related problems. Our opinion is that the patient should take part in choosing between a bioprosthesis and a mechanical prosthesis. This critical choice will depend upon the relative importance for each individual of an improved quality of life with a bioprosthesis versus a lower risk of reoperation with a mechanical valve.