Related Experiment Video
Updated: Aug 8, 2026

Evaluation of Planar-Cell-Polarity Phenotypes in Ciliopathy Mouse Mutant Cochlea
Published on: February 21, 2016
Development of the epithelium of the middle ear. Electron microscopic study of fine structure, including junctional
Abstract:
A detailed light and electron microscopic study of the development of the middle ear lining epithelium of the rat was undertaken in order to determine whether a portion of the middle ear lining is normally derived from a condensation of mesenchymal connective tissue. We learned that pharyngeal epithelium outpouches early in development and persists during the formation and growth of the ossicles and inner ear structures in a relatively constant anatomic relationship. We found no evidence of a contribution of mesodermal tissue to the lining epithelium itself. Certain features of the junctional complexes between adjacent cells were used as a means of identifying pharyngeal and middle ear epithelial cells. It is concluded that at no time is connective tissue found within the middle ear space (as defined by its epithelial limits); pneumatization occurs by absorption of mesenchymal tissue that occupied the space between the outer part of the epithelium and bone structures.
Related Concept Videos
Assembly of Complex Microtubule Structures
Basal Lamina are the Specialized Form of ECM
Proteins...
Classification of Epithelial Tissues: Simple Epithelium
Because of the thinness of the cells, simple squamous epithelium is present where the rapid passage of chemical compounds is observed. For example, the endothelium that lines the capillaries and vessels...
Classification of Epithelial Tissues: Stratified Epithelium
The Auditory Ossicles
The aptly named stapes look very much like a stirrup. The three ossicles are unique to mammals, and each plays a role in...
Anatomy of the Ear

