A relationship between erythrocyte volume and concentration in humans and other mammals

In 33 male and female human blood samples, red cell count decreased in a highly significant (p < 0.01) non-linear fashion as MCV increased. An identical, equally significant relationship was obtained using published hematologic values for 20 other mammalian species. These findings suggest a hyperbolic relationship between RCC and MCV, with the latter as the independent variable.