Organization of GABA-containing neurons in some extrapyramidal nuclei

Nuclei of the extrapyramidal system contain among the highest levels of GABA and its synthesizing enzyme glutamic acid decarboxylase (GAD) in the central nervous system. In recent years the anatomical organization of GABAergic neurons in the extrapyramidal experimental system has been the subject of considerable experimental enquiry. In this note, current knowledge concerning the origin and projections of GABAergic neurons in certain extrapyramidal nuclei is briefly reviewed.