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Dirhythmic breathing

G Flemister, N B Goldberg, J T Sharp

    Chest
    |January 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Dirhythmic breathing, characterized by two simultaneous respiratory rhythms, was observed in severe chronic obstructive lung disease patients. This phenomenon involves coordinated inspiratory muscle action, suggesting conflicting neural stimuli.

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    Area of Science:

    • Pulmonology
    • Respiratory Physiology
    • Neuroscience

    Background:

    • Severe chronic obstructive lung disease (COPD) patients often experience respiratory distress.
    • Respiratory failure in COPD can involve complex physiological adaptations.

    Purpose of the Study:

    • To describe a novel respiratory pattern termed dirhythmic breathing.
    • To investigate the mechanisms underlying dirhythmic breathing in COPD patients with respiratory failure.

    Main Methods:

    • Case study of four patients with severe COPD and recent respiratory failure.
    • Utilized magnetometer measurements of thoracoabdominal motion.
    • Performed simultaneous electromyograms of multiple inspiratory muscles.

    Main Results:

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    • Identified two distinct, simultaneous respiratory rhythms (8-13 breaths/min and 39-65 breaths/min).
    • Magnetometry and electromyography indicated coordinated action of inspiratory muscles for both rhythms.
    • Dirhythmic breathing appears to result from conflicting neural stimuli on respiratory centers.

    Conclusions:

    • Dirhythmic breathing is a newly identified respiratory phenomenon in severe COPD.
    • This pattern involves complex coordination of inspiratory muscles.
    • Conflicting neural inputs likely drive the dual respiratory rhythms observed.