Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Patterns of cellular proliferation during thyroid organogenesis

M S Smuts, S R Hilfer, R L Searls

    Journal of Embryology and Experimental Morphology
    |December 1, 1978
    PubMed
    Summary

    Chick thyroid development involves cell division and shape changes. New thyroid tissue grows by incorporating cells from surrounding tissues, with younger areas showing higher cell division rates.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The impact of backboard size and orientation on sternum-to-spine compression depth and compression stiffness in a manikin study of CPR using two mattress types.

    Resuscitation·2011
    Same author

    Cellular dynamics during evagination of the thyroid primordium in the chick embryo.

    The Anatomical record·2001
    Same author

    A role for neural cell adhesion molecule in the formation of the avian inner ear.

    Developmental dynamics : an official publication of the American Association of Anatomists·1998
    Same author

    Morphogenesis of the lung: control of embryonic and fetal branching.

    Annual review of physiology·1996
    Same author

    Involvement of extracellular matrix in the formation of the inner ear.

    Developmental dynamics : an official publication of the American Association of Anatomists·1995
    Same author

    Organization of tracheal epithelium in the cartilaginous portion of adult rabbit and its persistence in organ culture.

    The Anatomical record·1994

    Area of Science:

    • Developmental Biology
    • Cell Biology
    • Anatomy

    Background:

    • The chick thyroid gland undergoes significant shape changes during development.
    • Understanding the cellular mechanisms driving these morphological transformations is crucial.

    Purpose of the Study:

    • To investigate the relationship between cellular proliferation rates and locations and the shape changes in the developing chick thyroid.
    • To determine if localized cell division influences thyroid morphogenesis.

    Main Methods:

    • Utilized pulse labeling with tritiated thymidine to track cellular proliferation.
    • Analyzed the labeling index and cell positions within the chick thyroid and adjacent pharyngeal epithelium.
    • Compared proliferation rates in newly acquired versus older regions of the evaginating thyroid.

    Main Results:

    • The overall labeling index of the chick thyroid decreases as development progresses.
    • The developing thyroid initially shows a lower labeling index than the pharyngeal epithelium.
    • The thyroid grows by annexing cells from the pharyngeal epithelium, with newly incorporated regions exhibiting higher labeling indices than older regions.

    Conclusions:

    • Chick thyroid morphogenesis is influenced by localized cell division and the incorporation of cells from the pharyngeal epithelium.
    • Proliferation rates vary within the developing gland, with younger, annexing regions being more proliferative.

    Related Experiment Videos