Comparative studies on acid phosphatase isozymes of developing human placenta and fetal liver

Acid phosphatases from human placenta and fetal liver during ontogenic development have been studied by electrophoresis on polyacrylamide gels. Three isozymes have been detected in liver as well as in early and term placenta, and one more in placenta at mid-gestation. These isozymes behaved differentially towards heat and a number of inhibitors at different weeks of gestation. Quantitative determination of each isozyme also showed stage-specific variation.