[Effect of anesthetics on the cardiac chronotropic reactions induced by isoproterenol]

Some anesthetics were shown to diminish the intensity of positive chronotropic reactions of the cat heart induced by isoproterenol. As measured by the effect exerted, the anesthetics tested can be ranged as follows: a mixture of urethane and alpha-chloralose > nembutal > hexenal > urethane, alpha-chloralose, ether. Ftorotan does not affect the intensity of these reactions. By the effect intensity urethane, alpha-chloralose, ether, hexenal and nembutal correspond with that of practolol in a dose of 15 mg/kg, while the mixture or urethane and alpha-chloralose with that of practolol in a dose of 30 mg/kg.