[Electron microscopic study of the antiviral action of bonafton in experimental influenza infection]
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Updated: Aug 17, 2026

Using Zebrafish Models of Human Influenza A Virus Infections to Screen Antiviral Drugs and Characterize Host Immune Cell Responses
Published on: January 20, 2017
Abstract:
Action of bonaphthon on influenza A virus was studied in experimental influenzal pneumonia of mice. Bonaphthon was shown to lower 1.5-2 fold the reproduction of influenza virus in pulmonary tissue as compared with control. It is suggested that the mechanism of bonaphthon action may be due both to the inhibition of the synthesis of virus-specific membrane protein by the cells and to disordered transport of this polypeptide to the cell membranes. Bonaphthon proved to exert the most favorable effect in the course of its preventive administration in the early stages of infection.
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