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Updated: May 5, 2026

Assessment of the Metabolic Effects of Isocaloric 2:1 Intermittent Fasting in Mice
Published on: November 27, 2019
Consuming capacity for single meals in humans after a 24-hour fast
Abstract:
Self-selected, ad libitum meals were repeatedly fed to 5 healthy male subjects in order to empirically assess the influence of various intravenous and intraduodenally delivered solutions on food consumption. The solutions included i.v. and i.d. saline, i.v. and i.d. glucose, and i.v. autologous plasma feedings which had been previously obtained from the subjects after feeding or fasting states. Each subject had 11 meals under the various conditions. Liquid and solid food intakes in grams and calories were measured with each meal. No significant mean differences in food consumption were detected between the various i.v. and i.d. conditions; hence, food consumption for all meals was combined for the 5 subjects. Significant individual differences in food intakes were found that could not be correlated with body size, gastric emptying rates, or with the capacity to secrete gastric acid.
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