A serological proof of adiaspiromycosis in wild rodents

Using serological and histological methods, we examined 92 specimens of small, wild rodents (Apodemus sylvaticus, Clethrionomys glareolus, Micromys minutus, Microtus agrestis, M. arvalis, Mus musculus and Pitymys subterraneus) for the incidence of adiaspiromycosis. In addition, we examined 16 white, laboratory mice after their exposure to a natural biotope in which the incidence of adiaspiromycosis had been confirmed earlier. The results of serological tests were in correlation with those obtained with histological methods. While the immunodiffusion test showed a discrepancy of 6% only between the two methods, this was 19% for the complement fixation test. In animals with a negative histological finding, the immunodiffusion test confirmed antibodies in 3% the CF-test in 11%. An evident from results of serological methods, these might play an important role in the diagnosis of a spontaneous adiaspiromycosis even in wild rodents.