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Pseudoarthrosis in ankylosing spondylitis

S P Pastershank, D Resnick

    Journal of the Canadian Association of Radiologists
    |December 1, 1980
    PubMed
    Summary

    Pseudoarthrosis in ankylosing spondylitis involves spinal fractures and vertebral destruction. This condition is characterized by bony sclerosis adjacent to the damaged areas.

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    Area of Science:

    • Orthopedics
    • Rheumatology
    • Spinal Surgery

    Background:

    • Ankylosing spondylitis (AS) is a chronic inflammatory disease primarily affecting the spine.
    • Pseudoarthrosis, a type of non-union fracture, can complicate the management of spinal deformities in AS.
    • Understanding the specific pathology of spinal pseudoarthrosis in AS is crucial for effective treatment.

    Purpose of the Study:

    • To define the pathological characteristics of pseudoarthrosis in the spine specifically within the context of ankylosing spondylitis.
    • To elucidate the imaging findings associated with spinal pseudoarthrosis in AS patients.

    Main Methods:

    • Review of relevant literature on spinal pseudoarthrosis and ankylosing spondylitis.
    • Analysis of radiological and pathological features described in case studies and series.
    • Synthesis of diagnostic criteria and pathognomonic signs.

    Main Results:

    • Pseudoarthrosis of the spine in AS is characterized by a fracture extending through the intervertebral disc and neural arch.
    • Vertebral body end-plate destruction is a key feature.
    • Adjacent bony sclerosis is consistently observed around the fracture site.

    Conclusions:

    • Spinal pseudoarthrosis in ankylosing spondylitis presents a distinct pathological pattern involving fracture and vertebral destruction.
    • Radiological identification of vertebral end-plate destruction and bony sclerosis aids in diagnosis.
    • Further research into the biomechanics and treatment of this specific complication is warranted.

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