Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Acrosclerosis associated with vibration: an electron microscopic study

K Hashimoto, R S Craig

Journal of Cutaneous Pathology

|December 1, 1980

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Production of phytochelatins in Polygonum cuspidatum on exposure to copper but not to zinc.

Journal of pharmacobio-dynamics·1992

Same author

[A case report of pulmonary embolectomy for acute pulmonary embolism].

Kyobu geka. The Japanese journal of thoracic surgery·1992

Same author

Transient bullous dermolysis of the newborn. Retention of anchoring fibril- and basal lamina-like structures in keratinocytes and evidence of collagenolysis.

Journal of cutaneous pathology·1992

Same author

Activation of phospholipases in platelets by polyclonal antibodies against a surface membrane protein.

Biochimica et biophysica acta·1992

Same author

The growth regulation of keratinocytes.

The Journal of dermatology·1992

Same author

The role of growth factor in wound healing.

The Journal of dermatology·1992

Same journal

Diagnostic Challenge of a White Plaque on the Gingiva: Case Report of Glycogenic Acanthosis.

Journal of cutaneous pathology·2026

Same journal

Elevated IL-4 and IL-13 Expression in Hailey-Hailey Disease: Evidence for Th2-Mediated Pathogenesis and Targeted Treatment.

Journal of cutaneous pathology·2026

Same journal

Blastic Plasmacytoid Dendritic Cell Neoplasm.

Journal of cutaneous pathology·2026

Same journal

Atypical Grover Disease Associated With Merkel Cell Carcinoma: A Novel Paraneoplastic Presentation.

Journal of cutaneous pathology·2026

Same journal

Profile of a Founder: Herbert Zachareus Lund.

Journal of cutaneous pathology·2026

Same journal

The National Resident Match Program Arrives in Dermatopathology: 15 Years of Resilient Advocacy by the American Society of Dermatopathology's Fellowship Training Program Directors' Committee.

Journal of cutaneous pathology·2026

See all related articles

Vibration-induced acrosclerosis involves skin and nerve damage. Electron microscopy revealed collagen buildup and nerve degeneration, explaining the condition's symptoms.

Area of Science:

Pathology
Electron Microscopy
Dermatology

Background:

Vibration-induced acrosclerosis is a condition affecting individuals exposed to excessive mechanical vibrations.
The underlying pathological mechanisms require detailed investigation.

Observation:

A case of vibration-induced acrosclerosis was examined using electron microscopy.
Tissue samples from the dermis, vascular walls, and peripheral nerves were analyzed.

Findings:

Increased collagen deposition was observed in the dermis, vascular walls, and nerve surrounding tissues (peri- and endoneurium).
Vascular endothelial cells showed severe vacuolization and an increased number of lysosomes.
Peripheral nerves exhibited axonal degeneration and demyelination.

Related Experiment Videos

Implications:

These ultrastructural changes provide an organic basis for the sclerosis and neuropathies seen in vibration-induced acrosclerosis.
Understanding these cellular changes may inform future diagnostic or therapeutic strategies.