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Bronchogenic carcinoma associated with chronic lymphatic leukemia
Journal of the American Geriatrics Society
|January 1, 1981
Summary
Elderly patients with chronic lymphatic leukemia may develop lung cancer (bronchogenic carcinoma) years after diagnosis. New lung lesions in these patients warrant immediate investigation for malignancy.
Area of Science:
- Oncology
- Hematology
- Pulmonary Medicine
Background:
- Chronic lymphatic leukemia (CLL) is a hematologic malignancy.
- Bronchogenic carcinoma is a type of lung cancer.
Observation:
- Four elderly patients with CLL developed bronchogenic carcinoma.
- Radiologic lung abnormalities appeared 30-60 months after CLL diagnosis.
- Abnormalities were primarily in upper lobes and hili, often spreading to lymph nodes.
Findings:
- Lung cancer development in CLL patients is associated with a rapid decline.
- Average survival after lung carcinoma diagnosis was 2 months.
Implications:
- Pulmonary lesions in CLL patients should raise suspicion for malignancy.
- Prompt investigation of new lung lesions in CLL patients is crucial for timely diagnosis and management.