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Related Experiment Videos

Incidental pituitary adenomas

A D Parent, J Bebin, R R Smith

    Journal of Neurosurgery
    |February 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Occult pituitary adenomas were found in 8.5% of autopsy pituitary glands. These incidental pituitary tumors are often clinically unrecognized and appear to have a benign clinical course.

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    Area of Science:

    • Endocrinology
    • Pathology
    • Oncology

    Background:

    • Pituitary adenomas are common endocrine tumors.
    • Many pituitary adenomas remain clinically silent and are discovered incidentally.

    Purpose of the Study:

    • To determine the prevalence of occult pituitary adenomas in autopsy specimens.
    • To correlate the findings with clinical symptomatology and patient demographics.

    Main Methods:

    • Review of 500 consecutive autopsy pituitary glands.
    • Correlation of pathological findings with available clinical information.

    Main Results:

    • 42 occult pituitary adenomas identified (8.5% prevalence).
    • Tumors most frequent in the 6th and 7th decades, without sex predilection.

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  • Associated conditions included obesity (48%), hypertension (57%), and diabetes mellitus (11%).
  • Most tumors were small (1-15 mm) and located peripherally.
  • Only one case had prior clinical suspicion of a pituitary lesion.

    • Conclusions:

    • Occult pituitary adenomas are relatively common findings at autopsy.
    • The clinical and etiological significance remains unclear.
    • The clinical course appears to be benign.