[Effects of CT 1341 (althesin) anesthesia on human adrenal cortical function]

Following a short introduction on the stress action of anaesthetics, the effects of anaesthesia with CT 1341 (Althesin) on cortico-adrenal function was investigated, with an evaluation of cortisone plasma concentration. The results obtained in 10 patients point to an increase in plasma cortisone after 30 and 150 minutes of anaesthesia. The discussion hypothesizes the possible influences of the anaesthetic on the hypophyseal-adrenal axis.