[Presumed natural history of peritonitis caused by encapsulating membranes. Clinical aspects and therapy]

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Updated: Oct 9, 2026

Colon Ascendens Stent Peritonitis (CASP) - a Standardized Model for Polymicrobial Abdominal Sepsis
06:45

Colon Ascendens Stent Peritonitis (CASP) - a Standardized Model for Polymicrobial Abdominal Sepsis

Published on: December 18, 2010

M Franzini, G Sgarbi, S Bronzoni

    Minerva Chirurgica
    |November 15, 1980
    PubMed

    Insights

    Encapsulating peritonitis, a rare condition, is decreasing likely due to reduced tuberculosis spread. Surgical intervention is key for treating intestinal obstruction caused by this disease.

    Area of Science:

    • Gastroenterology
    • Abdominal Surgery
    • Pathology

    Background:

    • Encapsulating peritonitis is a rare condition characterized by fibrous encapsulation of the intestines.
    • Its pathogenesis and evolution remain poorly understood, with only approximately 200 reported cases globally.
    • A potential decrease in incidence may be linked to the declining prevalence of tuberculosis.

    Observation:

    • The condition involves the formation of multi-layered, poorly cellular connective tissue membranes on the intestinal peritoneum.
    • Inflammatory ascites often precedes the development of these encapsulating membranes.
    • Mechanical intestinal obstruction is a critical complication.

    Findings:

    • Capsulating membranes appear to originate from a layered connective tissue deposition on the peritoneum.
    • The condition is typically diagnosed incidentally during surgery or autopsy.
    • Surgical removal of the obstructing membranes and adhesions is the primary treatment.

    Implications:

    • Understanding the pathogenesis is crucial for developing targeted therapies.
    • Early surgical intervention can alleviate mechanical obstruction and improve patient outcomes.
    • Continued surveillance is necessary to monitor trends in this rare disease.

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