[Specific cellular immunity indices in acute leukemia in children]

Studies on the cell immunity in patients with acute leukemia were conducted in two functionally different tests: in cytotoxic reaction of lymphocytes and in the reaction of inhibition of leucocytes adherence which manifest accordingly the killer and antigen-reactive function of immunocompetent cells. There was found a statistically reliable enhancement of lymphocytes reactivity in patients with acute leukemia against leukemia-associated antigens compared with lymphocytes of healthy donors. The cytotoxic activity of lymphocytes was enhanced during the complete remission and before the recurrence, whereas the potential of antigen-reactive cells was reduced during the complete remission and against the background of the recurrence.