[Coagulation properties of the extravascular fluid. I. Coagulation factors in thoracic-duct lymph]

All coagulation factors could be found in the thoracic duct lymph of dogs, but the coagulation activities are significantly lower than that of plasma. Analysis of thoracic duct lymph shows that the activity components are significantly lower for factors I (30%), II (60%), V (20%), VII (50%), VIII (30%), IX (25%), X (70%) and factor XIII (30%). With global (TEG) and group test (PTT, thrombin time) various coagulation properties could be detected in blood and lymph. Antithrombin III reached two third of the plasma concentration. The prothrombin consumption in lymph was markedly reduced. The most remarkable result appears to be a certain quantitative modification of the individual factors in the lymph in comparison to those in blood. Although the lymph does not contain any thrombocytes, thromboplastin formation is sufficient for clot formation.