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[Use of lithium carbonate to treat Kugelberg--Welander spinal amyotrophy]
Abstract:
On the basis of data on disturbances of the metabolism of cyclic 3',5'-adenosine monophosphate in patients with Kugelberg-Welander's amyotrophy it is suggested that lithium carbonate which is an inhibitor of adenylcyclase should be used as a medicine. It was shown that the drug exerted a stabilizing influence on the pathological process. Positive clinical and biochemical changes due to the application of lithium carbonate are noted.