Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Right ventricular performance in mitral stenosis

E Wroblewski, F James, J F Spann

    The American Journal of Cardiology
    |January 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The future fate of Somali upwelling productivity and the implications for fisheries under climate change.

    Scientific reports·2026
    Same author

    Generalised absence seizures in Cavalier King Charles Spaniels presenting with paroxysms: eight cases (2016-2025).

    The Journal of small animal practice·2026
    Same author

    Frequency of non-generalized tonic clonic seizures in a referral population of dogs.

    Veterinary journal (London, England : 1997)·2023
    Same author

    Post operative synovial sepsis following endoscopic surgery: Increased risk associated with the carpal sheath.

    Equine veterinary journal·2015
    Same author

    Asparagine metabolism and nitrogen distribution during protein degradation in sugar-starved maize root tips.

    Planta·2013
    Same author

    Congestive heart failure. Biochemical and physiological considerations. Combined clinical staff conference at the National Institutes of Health.

    Annals of internal medicine·2013
    Same journal

    Real-World Effectiveness and Tolerability of Sacubitril/Valsartan in Octogenarian Patients With Heart Failure: Results From the PARACHUTER Study.

    The American journal of cardiology·2026
    Same journal

    ECG-Guided Conduction Pathways as a Lever to Shorten Post-TAVI Hospitalization.

    The American journal of cardiology·2026
    Same journal

    Cystatin-C versus creatinine and kidney function in heart failure with preserved ejection fraction: a SOGALDI-PEF analysis.

    The American journal of cardiology·2026
    Same journal

    Balloon-expandable versus Self-expanding Valves in Patients with Small Aortic Annuli Undergoing Transcatheter Aortic Valve Replacement.

    The American journal of cardiology·2026
    Same journal

    Drug-Coated Balloons versus Drug-Eluting Stents following Coronary Atherectomy in Severely Calcified Lesions: A Systematic Review and Meta-Analysis.

    The American journal of cardiology·2026
    Same journal

    Prehospital Statin Therapy and Outcomes in ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention.

    The American journal of cardiology·2026
    See all related articles

    Patients with mitral stenosis and pulmonary hypertension maintain normal right ventricular function, size, and ejection fraction despite elevated systolic pressure. This indicates preserved right ventricular performance in this condition.

    Area of Science:

    • Cardiology
    • Cardiovascular Physiology
    • Medical Imaging

    Background:

    • Right ventricular (RV) function in mitral stenosis (MS) with pulmonary hypertension (PH) was not well understood.
    • Dynamic geometry and pump function of the RV in this patient group required further definition.

    Purpose of the Study:

    • To define the dynamic geometry and pump function of the pressure-overloaded RV in patients with MS and PH.
    • To assess RV performance using a novel method for volume calculation.

    Main Methods:

    • Utilized computer-analyzed biplane right ventriculograms to assess RV performance.
    • Calculated RV end-diastolic volume index and ejection fraction in normal subjects and MS patients.
    • Analyzed RV stroke work and stroke volume against end-diastolic volume.

    Related Experiment Videos

    Main Results:

    • MS patients had elevated systolic RV pressure but normal RV end-diastolic volume index and ejection fraction.
    • RV stroke work vs. end-diastolic volume slope was steeper in MS patients.
    • RV stroke volume vs. end-diastolic volume plot showed similar performance between groups, indicating normal RV function.
    • Left ventricular ejection fraction was reduced in MS patients.

    Conclusions:

    • The right ventricle performs normally in patients with mitral stenosis and moderate pulmonary hypertension.
    • The RV maintains normal size and ejection fraction despite increased afterload.
    • Reduced left ventricular function was observed in mitral stenosis patients.