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Related Experiment Videos

Current concepts of esophageal function

G W Meyer, D O Castell

    American Journal of Otolaryngology
    |November 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Esophageal manometry uses perfused or nonperfused systems to measure pressures. Findings reveal asymmetrical pressure profiles in the upper and lower esophageal sphincters, with symmetrical peristaltic pressures in the esophagus body.

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    Area of Science:

    • Gastroenterology
    • Physiology

    Background:

    • Esophageal manometry is crucial for assessing esophageal function.
    • Current methods include nonperfused probes and perfused catheter systems.

    Purpose of the Study:

    • To describe current esophageal manometry techniques.
    • To detail pressure profiles of esophageal sphincters and peristalsis.
    • To discuss the physiology of swallowing and lower esophageal sphincter control.

    Main Methods:

    • Utilized perfused catheter systems with low-compliance pumps and 0.8 mm diameter catheters.
    • Analyzed intraluminal pressure data from esophageal manometry.

    Main Results:

    • Upper esophageal sphincter pressure is asymmetrical (higher anterior/posterior than lateral).

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  • Lower esophageal sphincter pressure is asymmetrical (higher left/left posterior).
  • Peristaltic pressures in the esophageal body are symmetrical.

    • Conclusions:

    • Esophageal manometry reveals distinct pressure patterns in sphincters and the esophageal body.
    • Lower esophageal sphincter exhibits constant contraction, relaxing upon vagal nerve stimulation.
    • Mechanisms controlling the lower esophageal sphincter require further elucidation.