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Updated: Aug 1, 2026

Auditory Brainstem Response and Outer Hair Cell Whole-cell Patch Clamp Recording in Postnatal Rats
Published on: May 24, 2018
Organ of Corti-specific polypeptides: OCP-I and OCP-II
Abstract:
Two polypeptides, OCP-I and OCP-II, specific to the organ of Corti of the quinea pig and the rate, were detected by two-dimensional polyacrylamide gel electrophoresis. They were neither present in other inner ear structures, nor in other organs tested. The two polypeptides constitute a substantial portion of the total protein of the organ of Corti. Both inner and outer layer of the organ of Corti contained approximately equal amounts of OCP-I and OCP-II. The molecular weights of OCP-I and OCP-II are 37,000 and 22,500 daltons, respectively. The corresponding pI values are 4.9 and 5.1, respectively. in addition, actin and tubulin were detected in both layers of the organ of Corti.
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